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Food Funct 5(12):32163223 Hsieh F-C, Lee C-L, Chai C-Y, Chen W-T, Lu Y-C, Wu C-S (2013) Oral administration of Lactobacillus reuteri GMNL-263 improves insulin resistance and ameliorates hepatic steatosis in high fructose-fed rats

A 28-day administration of BPC 157 (4, 1, or 0.2 mg/kg/day, i.m.) in rats and (2, 0.5, or 0.1 mg/kg/day) in beagle dogs also resulted in no apparent changes as compared to saline-treated animals

Still, the agency says the market remains stable and plan offerings are robust

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Most side effects are mild and improve over time

[110] Hormonal effects represent a potential concern, particularly with long-term melatonin use